Victoria Police is appealing for public assistance to help locate missing South Australian woman Colleen South.

The 58-year-old Renown Park, Adelaide, woman was reported missing in South Australia after she was last seen driving a 2006 silver Hyundai Getz sedan at Renown Park on Friday 1st July around 3.30pm.

The Hyundai was located abandoned in a ditch off Mackies Road, Bunguluke 15kms east of Wycheproof, on Sunday 3rd July.

Victoria Police commenced a comprehensive search of dense bushland in the surrounding area conducting Air Wing and drone searches along with Mounted Branch, Dog Squad, officers on foot and in vehicles along with SES.

Local farmers were also asked to check buildings and sheds on their properties.

Police and family have concerns for Colleen as she has a medical condition and her disappearance is out of character.

Colleen is about 154cm tall, of solid build, and has brown hair and green eyes.

She was last seen wearing a black and white striped shirt with blue jeans.

The search for Colleen continues with patrols conducted by local units and highway patrol with oversight by the Search and Rescue Squad.

At this stage, Colleen’s disappearance is not being treated as suspicious.

Police have released an image of Colleen and urge anyone who sights her or with any information on her whereabouts to contact Swan Hill Police Station on (03) 5036 1600.